Modeling the Budding Yeast Cell Cycle

GAL-ESP1 cdc20-ts

debug: ,
test user =
test db =

Simulation:

Change of parameters: ks20'=ks20"=0, ESP1T=20 (=20X WT), MDT=150.
Arrest: Telophase arrest.

Experiments:

Ciosk, R., Zachariae, W., Michaelis, C., Shevchenko, A., Mann, M. and Nasmyth, K. (1998). An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell 93:1067-1076.
[Abstract] [Article]
Experimental results: Sister chromatids separate, Clb2 may not be degraded.
Comments: